2009

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Petnicki-Ocwieja T, Hrncir T, Liu YJ, Biswas A, Hudcovic T, Tlaskalova-Hogenova H, Kobayashi KS.

Nod2 is required for the regulation of commensal microbiota in the intestine.
Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15813-8.

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Matza D, Badou A, Jha MK, Willinger T, Antov A, Sanjabi S, Kobayashi KS, Marchesi VT, Flavell RA.
Requirement for AHNAK1-mediated calcium signaling during T lymphocyte cytolysis.
Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9785-90.

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Sicard P, Jacquet S, Kobayashi KS, Flavell RA, Marber MS.
Pharmacological postconditioning effect of muramyl dipeptide is mediated through RIP2 and TAK1.
Cardiovasc Res. 2009 Jul 15;83(2):277-84.

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Rosenzweig HL, Jann MM, Glant TT, Martin TM, Planck SR, van Eden W, van Kooten PJ, Flavell RA, Kobayashi KS, Rosenbaum JT, Davey MP.
Activation of nucleotide oligomerization domain 2 exacerbates a murine model of proteoglycan-induced arthritis.
J Leukoc Biol. 2009 Apr;85(4):711-8.

 

 

2008

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Shin S, Case CL, Archer KA, Nogueira CV, Kobayashi KS, Flavell RA, Roy CR, Zamboni DS.
Type IV secretion-dependent activation of host MAP kinases induces an increased proinflammatory cytokine response to Legionella pneumophila.
PLoS Pathog. 2008 Nov;4(11):e1000220.

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Divangahi M, Mostowy S, Coulombe F, Kozak R, Guillot L, Veyrier F, Kobayashi KS, Flavell RA, Gros P, Behr MA.
NOD2-deficient mice have impaired resistance to Mycobacterium tuberculosis infection through defective innate and adaptive immunity.
J Immunol. 2008 Nov 15;181(10):7157-65.

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Rosenzweig HL, Martin TM, Planck SR, Galster K, Jann MM, Davey MP, Kobayashi K, Flavell RA, Rosenbaum JT.
Activation of NOD2 in vivo induces IL-1beta production in the eye via caspase-1 but results in ocular inflammation independently of IL-1 signaling.
J Leukoc Biol. 2008 Aug;84(2):529-36.

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Rosenzweig HL, Martin TM, Jann MM, Planck SR, Davey MP, Kobayashi K, Flavell RA, Rosenbaum JT.
NOD2, the gene responsible for familial granulomatous uveitis, in a mouse model of uveitis.
Invest Ophthalmol Vis Sci. 2008 Apr;49(4):1518-24.

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Jacquet S, Nishino Y, Kumphune S, Sicard P, Clark JE, Kobayashi KS, Flavell RA, Eickhoff J, Cotten M, Marber MS.
The role of RIP2 in p38 MAPK activation in the stressed heart.
J Biol Chem. 2008 May 2;283(18):11964-71.

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Matza D, Badou A, Kobayashi KS, Goldsmith-Pestana K, Masuda Y, Komuro A, McMahon-Pratt D, Marchesi VT, Flavell RA.
A scaffold protein, AHNAK1, is required for calcium signaling during T cell activation.
Immunity. 2008 Jan;28(1):64-74.

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Wilmanski JM, Petnicki-Ocwieja T, Kobayashi KS.
NLR proteins: integral members of innate immunity and mediators of inflammatory diseases.
J Leukoc Biol. 2008 Jan;83(1):13-30.

 

 

2007

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Pan Q, Mathison J, Fearns C, Kravchenko VV, Da Silva Correia J, Hoffman HM, Kobayashi KS, Bertin J, Grant EP, Coyle AJ, Sutterwala FS, Ogura Y, Flavell RA, Ulevitch RJ.
MDP-induced interleukin-1beta processing requires Nod2 and CIAS1/NALP3.
J Leukoc Biol. 2007 Jul;82(1):177-83.

 

 

2006

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Deng JC, Cheng G, Newstead MW, Zeng X, Kobayashi K, Flavell RA, Standiford TJ.
Sepsis-induced suppression of lung innate immunity is mediated by IRAK-M.
J Clin Invest. 2006 Sep;116(9):2532-42.

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Pan Q, Kravchenko V, Katz A, Huang S, Ii M, Mathison JC, Kobayashi K, Flavell RA, Schreiber RD, Goeddel D, Ulevitch RJ.
NF-kappa B-inducing kinase regulates selected gene expression in the Nod2 signaling pathway.
Infect Immun. 2006 Apr;74(4):2121-7.

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Shinohara ML, Lu L, Bu J, Werneck MB, Kobayashi KS, Glimcher LH, Cantor H.
Osteopontin expression is essential for interferon-alpha production by plasmacytoid dendritic cells.
Nat Immunol. 2006 May;7(5):498-506.

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Zamboni DS, Kobayashi KS, Kohlsdorf T, Ogura Y, Long EM, Vance RE, Kuida K, Mariathasan S, Dixit VM, Flavell RA, Dietrich WF, Roy CR.
The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection.
Nat Immunol. 2006 Mar;7(3):318-25.

 

 

2005

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Li H, Cuartas E, Cui W, Choi Y, Crawford TD, Ke HZ, Kobayashi KS, Flavell RA, Vignery A.
IL-1 receptor-associated kinase M is a central regulator of osteoclast differentiation and activation.
J Exp Med. 2005 Apr 4;201(7):1169-77.

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Kobayashi KS, Chamaillard M, Ogura Y, Henegariu O, Inohara N, Nuñez G, Flavell RA.
Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract.
Science. 2005 Feb 4;307(5710):731-4.

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2003

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​Kobayashi KS, Eynon EE, Flavell RA

​Intracellular debugging.

​Nat Immunol. 2003; 4:652-654

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2002

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​Kobayashi K, Hernandez LD, Galan JE, Janeway CA Jr, Medzhitov R, Flavell RA

IRAK-M is a negative regulator of Toll-like receptor signaling. 

Cell. 2002;110:191-202

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​Kobayashi K, Inohara N, Hernandez LD, Galan JE, Nunez G, Janeway CA, Medzhitov R, Flavell RA

RICK/Rip2/CARDIAK mediates signaling for receptors of the innate and adaptive immune systems. 

​Nature. 2002:416:194-9

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